Statistics on Somatic Variant Dataset Development

DB Release Release Date Variants Count Ref. Count Last Ref_ID Added Ref. Added Mutations Deleted Mutations* PubMed Search**
R3 - 10,411 1,048 1,075 - - - -
R4 July 2000 14,050 1,320 1,369 294 3,798 159 Jan 1998 - Apr 2000
R5 June 2001 15,121 1,412 1,480 111 1,459 388 May - Dec 2000
R6 Jan 2002 16,285 1,485 1,571 91 1,549 385 Jan - June 2001
R7 Sept 2002 17,689 1,599 1,715 144 1,477 73 July 2001 - June 2002
R8 June 2003 18,585 1,680 1,810 95 924 28 July 2002 - Feb 2003
R9 July 2004 19,809 1,769 1,921 111 1,196 40 March - Dec 2003
R10 July 2005 21,587 1,876 2,055 107 1,788 10 Jan - Dec 2004
R11 Nov 2006 23,544 1,995 2,221 120 2,014 57 Jan - Dec 2005
R12 Nov 2007 24,810 2,081 2,349 86 1,331 65 Jan - Dec 2006
R13*** Nov 2008 24,806 2,081 2,349 - - 4 -
R14 Nov 2009 26,597 2,179 2,483 98 1,814 - Jan - Dec 2007
R15**** Nov 2010 27,580 2,218 2,564 48 1,021 38 2,008 - 2009****
R16**** Nov 2012 29,575 2,279 2,635 71 1,995 - 2008 - 2011****
R17**** Nov 2013 29,711 2,285 2,641 6 136 - 2010 - 2013****
R18**** April 2016 29,893 2,306 2,642 1 182 NA -
These statistics are for all studies compiled in the IARC database (downloadable dataset of somatic mutations). Some of these data are not included in the searchable data because they have been identified as poor quality data (such studies are annotated as 'Exclude' and we recommended to exclude them from meta-analyses).

* Data may be deleted if (1) they correspond to duplicate entries or (2) errors. Publication of the same set of samples in different papers by the same authors is a serious problem that has led to duplicates entries in the database in the past. We now perform systematic searches of the database under the author’s name to identify earlier entries that may correspond to the same dataset. We have also extensively reviewed the entire dataset in order to find and eliminate these duplicates. However, despite these efforts, some duplicates may remain in the database and their identification is an ongoing task.
** Papers edited in PubMed at the indicated dates were searched with selected keywords and reviewed to extract relevant data.
*** The dataset of somatic variants has not been updated.
**** The update only include a selection of papers (see database developments).
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