Summary results may be found in the reviews and table below:
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TP53 somatic variants: prognostic and predicitve value in human cancers.
Olivier M. Chapter 8 in p53 in the Clinics.
Hainaut, Pierre; Olivier, Magali; Wiman, Klas (Eds.) 2013, VII, 544 p. 45 illus., Hardcover ISBN 978-1-4614-3675-1 Jan;2(1):a001008. - TP53 mutations in human cancers: origins, consequences, and clinical use. Olivier M, Hollstein M, Hainaut P. Cold Spring Harb Perspect Biol 2010 Jan;2(1):a001008. PubMed
| Tumor Site | Number of studies* reporting that TP53 mutations are: | ||
|---|---|---|---|
| Related to Bad Prognosis | Related to Good Prognosis | Not Related to Prognosis | |
| Bladder | 4 | - | 3 |
| Bones | 1 | - | 1 |
| Brain | 3 | 2 | 4 |
| Breast | 28 | 1 | 5 |
| Colorectum | 16 | - | 8 |
| Esophagus | 2 | - | 2 |
| Head & Neck | 7 | - | 2 |
| Hematol. | 12 | - | - |
| Larynx | - | - | 1 |
| Liver | 3 | - | - |
| Lung | 8 | - | 6 |
| Ovary | 7 | 1 | 2 |
| Pancreas | 1 | 1 | 1 |
| Prostate | 1 | - | 1 |
| Soft Tissues | 2 | - | - |
| Stomach | 1 | - | 2 |
| Renal Pelvis | 1 | - | - |
* Only studies with >50 cases were included.