TP53 Database: Search Cell-Line Data

Cell-Line Name

ATCC ID

COSMIC ID

TP53 Status

LOE

MUT

NULL

WT

Tumor Origin

Metastasis

Primary

Recurrent

Topography

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Morphology

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Start Material

DNA

DNA/RNA

RNA

Exon Analyzed

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cDNA Descriptions

i.e.: c.524G>A or 524G>A

Reference Sequence: NM_000546.5

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Protein Descriptions

i.e.: p.R175H or R175H

Reference Sequence: UniProt P04637

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Genomic Descriptions (hg19)

i.e.: g.7578406C>T or 7578406C>T

Reference Sequence: GenBank NC_000017.10

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Genomic Descriptions (hg38)

i.e.: g.7675088C>T or 7675088C>T

Reference Sequence: GenBank NC_000017.11

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Type

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Description

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Struct-Function Motif

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Exon/Intron

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Effect

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Transactivation Class

functional

non-functional

partially functional

supertrans

SIFT Class

Damaging

Tolerated

Chromosome Positioning

hg19

hg38

Mutant Base (coding)

Codon Number

Enter by Range

Codon No.

Start (≤)

to

(≤) End

Wild-Type Codon

Mutant Codon

Wild-Type Amino Acid

Mutant Amino Acid

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p53 Coding Sequence

Genetic Code

Age at Diagnosis

Start

to

End

Sex

Female

Male

Germline Variation

BRCA1

FHIT

NF1

Tobacco

non-smoker

smoker

Alcohol

Drinker

Non-Drinker

Country/Population

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Infectious Agent

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Exposure

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Be aware that many cell lines may have different TP53 status according to different studies.

This may be due to cell-line misidentification, cross-contamination or sequencing techniques (see PMID28127703, PMID24700732 for discussions on these issues).

We recommend also checking other available resources: